Thermo Fisher Scientific HEPACAM2 Polyclonal Antibody
HEPACAM2 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에서 사용 가능. Western Blot에 적합하며, 항원 친화 크로마토그래피로 정제됨. PBS 버퍼에 0.02% sodium azide 포함, 냉장 또는 냉동 보관 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 0.5–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 19 amino acid peptide near the carboxy terminus of human HEPACAM2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551832 |
Product Specific Information
- Suggested positive control: Mouse brain tissue lysate
- PA5-34480 can be used with blocking peptide PEP-1522
Target Information
HEPACAM2 (Hepatocyte cell adhesion molecule 2) is a type I N-linked transmembrane glycoprotein belonging to the immunoglobulin superfamily. The exact function of HEPACAM2 is currently unknown, but its related protein HEPACAM forms cis-homodimers on the cell surface to regulate cell adhesion and may inhibit cell growth through suppression of cell proliferation.
HEPACAM and HEPACAM2 mRNA are differentially regulated in canine tumors, with HEPACAM2 mRNA showing increased levels in adenomas but decreased levels in metastatic carcinomas compared to normal tissues, while HEPACAM protein levels decrease in adenomas.
It is likely that HEPACAM2 plays a distinct role from HEPACAM in tumor development and progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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