Thermo Fisher Scientific ISL1 Monoclonal Antibody (1H9)
ISL1 단백질을 검출하기 위한 Thermo Fisher Scientific의 마우스 단클론 항체. Western blot, IHC, ICC/IF, ELISA 등 다양한 응용에 적합. 인간 및 영장류 시료에 반응하며, 39kDa ISL1 단백질을 인식. 연구용으로만 사용 가능.
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Thermo Fisher Scientific ISL1 Monoclonal Antibody (1H9)
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Immunohistochemistry (IHC) | - | 3 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 | 1 publication |
| ELISA | 1:10,000 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Chimpanzee, Human, Non-human primate |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1H9 |
| Immunogen | Purified recombinant fragment of human ISL1 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_10975891 |
Product Specific Information
MA5-15515 targets ISL1 in indirect ELISA, IF, IHC, and WB applications and shows reactivity with human samples.
The immunogen is a purified recombinant fragment of human ISL1 expressed in E. coli.
This antibody detects ISL1, which has a predicted molecular weight of approximately 39 kDa.
Target Information
ISL1 encodes a LIM/homeodomain transcription factor that binds to enhancer regions of genes such as the insulin gene, playing a key role in insulin gene expression regulation.
It is essential for the development of pancreatic cell lineages and motor neuron generation.
Mutations in ISL1 have been linked to maturity-onset diabetes of the young.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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