Thermo Fisher Scientific Phospho-OCT1 (POU2F1) (Ser385) Polyclonal Antibody
POU2F1(OCT1) Ser385 인산화 형태를 특이적으로 검출하는 Rabbit Polyclonal Antibody. Western blot에 적합하며, 인산화된 OCT1의 내인성 수준을 탐지. 1 mg/mL 액상 형태, -20°C 보관. 연구용으로만 사용 가능.
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Thermo Fisher Scientific Phospho-OCT1 (POU2F1) (Ser385) Polyclonal Antibody
Applications
- Western Blot (WB): 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human POU2F1 (Accession P14859), corresponding to amino acid residues around phosphorylated Ser385 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817225 |
Product Specific Information
Antibody detects endogenous levels of POU2F1/OCT1 only when phosphorylated at Ser385.
Target Information
OCT1 (POU2F1) is a ubiquitously expressed transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of genes for small nuclear RNAs (snRNA), histone H2B, and immunoglobulins. It modulates transcription transactivation by NR3C1, AR, and PGR.
In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1, enabling transcription of viral immediate early genes.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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