Thermo Fisher Scientific Phospho-PKD2 (Ser812) Polyclonal Antibody
PKD2 단백질의 Ser812 인산화 부위를 특이적으로 인식하는 Rabbit Polyclonal 항체. Western blot에 적합하며, 인간, 마우스, 랫드, 영장류 시료에 반응. 1 mg/mL 농도의 액상 형태로, PBS 및 50% glycerol buffer에 보관. -20°C에서 장기 보관 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PKD2 (Accession Q13563), corresponding to amino acid residues around phosphorylated Ser812 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2817229 |
Product Specific Information
Antibody detects endogenous levels of PKD2 only when phosphorylated at Ser812.
Target Information
This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. It may function in renal tubular development, morphology, and function, and may modulate intracellular calcium homeostasis and other signal transduction pathways. This protein interacts with polycystin 1 to produce cation-permeable currents. Mutations in this gene have been associated with autosomal dominant polycystic kidney disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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