Thermo Fisher Scientific BAF53A Polyclonal Antibody
Goat 폴리클로날 항체로 인간 BAF53A 단백질을 인식합니다. Western blot에 적합하며 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며 TBS 버퍼에 0.5% BSA와 0.02% sodium azide를 포함합니다. 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide YEEGGKQCVERKCP, corresponding to C-terminal amino acids 416–429 of BAF53A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2257972 |
Product Specific Information
- Recommended positive controls: The peptide used to generate this antibody is available for purchase (GTX15718-PEP).
Target Information
BAF53A is a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, an ATP-binding cleft as a common feature. ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration, and chromatin remodeling.
This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, functionally related to the SWI/SNF complex in S. cerevisiae and Drosophila. The complex facilitates transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression.
Together with beta-actin, BAF53A is required for maximal ATPase activity of BRG1 and for the association of the BAF complex with chromatin/matrix. Three transcript variants encoding two different protein isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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