Thermo Fisher Scientific Lactoferrin Polyclonal Antibody
인간 Lactoferrin을 특이적으로 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF, IP 등 다양한 응용에 사용 가능. 항원 친화 크로마토그래피로 정제된 고품질 항체로 장기 보관 시 -20°C에서 안정적. 연구용으로만 사용.
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Thermo Fisher Scientific Lactoferrin Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (IHC) | 1:200 |
| Immunocytochemistry (ICC/IF) | 1:200 |
| Immunoprecipitation (IP) | 1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Purified full-length human native Lactoferrin protein (UniProt ID: P02788-1, range 1–710) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris glycine (pH 7.4–7.9), 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_1958282 |
Product Specific Information
PA1-31254 detects Lactoferrin from human samples.
Target Information
Lactoferrin (LF) is an iron-binding glycoprotein composed of a single ~80 kDa polypeptide chain folded into two homologous lobes, each capable of reversibly binding one ferric ion (Fe³⁺).
LF is found in external fluids such as milk and mucosal secretions and is a major component of neutrophil secondary granules.
It plays roles in:
- Regulation of iron homeostasis
- Host defense against microbial infections
- Anti-inflammatory activity
- Regulation of cellular growth and differentiation
- Protection against cancer development and metastasis
Lactoferrin efficiently binds and removes Fe³⁺ from its environment and also exhibits bactericidal and proteolytic activity.
Three isoforms (LTF-α, LTF-β, LTF-γ) have been identified. Receptors for LTF are expressed in the gastrointestinal tract, macrophages, lymphocytes, neutrophils, platelets, and certain bacteria.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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