
Thermo Fisher Scientific GRAF Polyclonal Antibody
Goat polyclonal antibody recognizing GRAF protein. Validated for WB and IHC(P) applications. Supplied as unconjugated liquid form at 0.5 mg/mL. Recommended for research use only, not for diagnostic purposes.
- 카탈로그번호
- PA131264
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 0.3–1 µg/mL
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 3.75 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide KTGLIPENYVEFL |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2059282 |
Product Specific Information
- Recommended positive controls: The peptide used to generate this antibody is available for purchase (GTX15916-PEP).
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase.
The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42.
Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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