Thermo Fisher Scientific BAIAP2 Polyclonal Antibody

Thermo Fisher Scientific BAIAP2 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Recommended positive control: The peptide used to generate this antibody is available for purchase (GTX15697-PEP).
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

The protein encoded by the BAIAP2 gene acts as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. It serves as an adaptor linking membrane-bound G-proteins to cytoplasmic effector proteins and functions as an insulin receptor tyrosine kinase substrate, suggesting a role for insulin in the central nervous system.
Additionally, it interacts with Rho small G protein effectors involved in stress fiber formation and cytokinesis. This protein contributes to lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. It also interacts with the dentatorubral-pallidoluysian atrophy gene, linked to an autosomal dominant neurodegenerative disease.
Alternative splicing results in multiple transcript variants encoding distinct isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.