Thermo Fisher Scientific BAIAP2 Polyclonal Antibody
BAIAP2 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체입니다. Western blot 및 파라핀 IHC에 적합하며, 비접합 액상 형태로 제공됩니다. 뇌 특이적 단백질 연구 및 세포 이동성, 신경 성장 관련 연구에 활용 가능합니다.
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Thermo Fisher Scientific BAIAP2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–3 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide SGSGTLVSTV (Human) (C-terminal) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Conditions | Store at 4°C for short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_1954661 |
Product Specific Information
- Recommended positive control: The peptide used to generate this antibody is available for purchase (GTX15697-PEP).
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by the BAIAP2 gene acts as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. It serves as an adaptor linking membrane-bound G-proteins to cytoplasmic effector proteins and functions as an insulin receptor tyrosine kinase substrate, suggesting a role for insulin in the central nervous system.
Additionally, it interacts with Rho small G protein effectors involved in stress fiber formation and cytokinesis. This protein contributes to lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. It also interacts with the dentatorubral-pallidoluysian atrophy gene, linked to an autosomal dominant neurodegenerative disease.
Alternative splicing results in multiple transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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