Thermo Fisher Scientific SMC1 Monoclonal Antibody (C2M)
Human SMC1 단백질을 인식하는 Mouse IgG1 단클론 항체로, WB 및 ICC/IF에 사용 가능. HeLa 세포를 양성 대조로 추천. 단백질 A/G로 정제된 액상 항체이며, -20°C에서 보관. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 5–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C2M |
| Immunogen | Recombinant protein corresponding to aa 402–894 of human SMC1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS |
| Contains | 0.08% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1087352 |
Product Specific Information
A suggested positive control for this product is HeLa cells.
Target Information
Structural Maintenance of Chromosomes (SMC) family proteins play critical roles in nuclear events requiring structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair, and global transcriptional repression.
SMC proteins are conserved in eukaryotes and their dysfunction leads to mitotic chromosome segregation defects, indicating their essential role in chromosome dynamics.
SMC1 and SMC3 form a heterodimeric complex necessary for metaphase progression and sister chromatid cohesion. Mutations in the SMC1 gene are associated with Cornelia de Lange syndrome 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: MA1-12604_SMC1_Q14683-1_House_mouse.svg, MA1-12604_SMC1_Q14683-1_House_mouse_PDP.jpeg, MA1-12604_SMC1_Q8NDV3-3_House_mouse.svg, MA1-12604_SMC1_Q8NDV3-3_House_mouse_PDP.jpeg)
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