Thermo Fisher Scientific MRP2 Monoclonal Antibody (M2 III-6)
MRP2 단백질을 검출하기 위한 Thermo Fisher Scientific의 Mouse Monoclonal Antibody입니다. Western blot, IHC, ICC 등 다양한 응용에 적합하며 Human 및 Rat 시료에서 반응합니다. PBS/BSA 버퍼에 보관되며 연구용으로 사용됩니다.
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- MA126536
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Thermo Fisher Scientific MRP2 Monoclonal Antibody (M2 III-6)
Applications and Tested Dilution
- Western Blot (WB): Assay-dependent
- Immunohistochemistry (Paraffin) (IHC-P): Assay-dependent
- Immunohistochemistry (Frozen) (IHC-F): Assay-dependent
- Immunocytochemistry (ICC/IF): Assay-dependent
Publications
- 1 publication available (refer to supplier reference list)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | M2 III-6 |
| Immunogen | Bacterial fusion protein of human MRP2 containing the carboxy-terminal region beginning with residue 202 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Purified |
| Storage Buffer | PBS with 1% BSA |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_794960 |
Product Specific Information
MA1-26536 detects multidrug resistance associated protein 2 (MRP2) from human samples.
Target Information
This gene encodes the prototype of the membrane-associated guanylate kinase (MAGUK) family proteins. MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intercellular junctions.
The encoded protein is an extensively palmitoylated membrane phosphoprotein containing:
- PDZ domain
- Src homology 3 (SH3) motif
- Guanylate kinase domain
This gene product interacts with various cytoskeletal and junctional proteins in different tissues and cell types, and may be involved in:
- Regulation of cell shape
- Hair cell development
- Neural patterning of the retina
- Apico-basal polarity
- Tumor suppression pathways in non-erythroid cells
Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(해당 항체 구조 및 Antigen 이미지: MA1-26536_MRP2_Q92887-1_House_mouse.svg, MA1-26536_MRP2_Q92887-1_House_mouse_PDP.jpeg)
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