Thermo Fisher Scientific MRP6 Monoclonal Antibody (M6II-31)
MRP6 단백질을 인식하는 Rat 모노클론 항체로, Western blot 및 면역조직화학(IHC/ICC)에 적합. 인간 시료 반응성 검증 완료. 비결합형 액상 형태이며 4°C 보관. 연구용으로만 사용 가능.
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Thermo Fisher Scientific MRP6 Monoclonal Antibody (M6II-31)
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:20–1:50 | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 | - |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:20–1:50 | - |
| Immunocytochemistry (ICC/IF) | 1:20–1:50 | - |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rat / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | M6II-31 |
| Immunogen | Bacterial fusion protein of human MRP6 containing amino acids 764–964, spanning the putative 12th transmembrane region and predicted internal/external regions of the protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Tissue culture supernatant with 1% BSA |
| Contains | 0.1% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
| RRID | AB_794964 |
Product Specific Information
Recommended positive controls: Liver, kidney, and cell lines (drug-sensitive parental cell lines and their multidrug-resistant derivatives).
Target Information
The protein encoded by this gene belongs to the ATP-binding cassette (ABC) transporter superfamily. ABC proteins mediate transport of various molecules across cellular membranes and are divided into seven subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White.
MRP6, a member of the MRP subfamily, is associated with multidrug resistance. Mutations in this gene cause pseudoxanthoma elasticum. Alternatively spliced transcript variants encoding different proteins have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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