Thermo Fisher Scientific S100 Monoclonal Antibody (4C4.9)

Applications

Tested Dilution

Publications

Western Blot (WB)

-

View 2 publications 2 publications

Immunohistochemistry (IHC)

-

View 52 publications 52 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:100

View 5 publications 5 publications

Immunohistochemistry (Frozen) (IHC (F))

1:50-1:100

-

Immunocytochemistry (ICC/IF)

Assay-dependent

-

Miscellaneous PubMed (Misc)

-

View 2 publications 2 publications

Product Specifications

Species Reactivity

Bovine, Human, Mouse, Non-human primate, Rat

Published species

Human, Mouse, Non-human primate, Rat

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

4C4.9

Immunogen

Purified bovine brain S100 protein.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

tissue culture supernatant

Contains

0.09% sodium azide

Storage conditions

4° C, do not freeze

Shipping conditions

Wet ice

RRID

AB_795376

Product Specific Information

This antibody stains S100 in Schwannomas, ependymomas, astrogliomas, almost all benign and malignant melanomas and their metastases. Immunostaining of formalin-fixed paraffin-embedded tissues require no special pretreatment. Use at a dilution of 1:50-1:100 for 30 minutes at room temperature. A suggested positive control for this product is melanoma.

Target Information

S100 belongs to the family of calcium binding proteins such as calmodulin and troponin C. S100A is composed of an alpha and beta chain whereas S100B is composed of two beta chains. S100 protein is also expressed in the antigen presenting cells such as the Langerhans cells in skin and interdigitating reticulum cells in the paracortex of lymph nodes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.