
Thermo Fisher Scientific Protein APC Recombinant Rabbit Monoclonal Antibody (5F2)
Protein APC 단백질을 타겟으로 하는 재조합 토끼 단클론 항체로, WB 및 IHC(Paraffin) 실험에 적합합니다. 고순도 Affinity chromatography로 정제되었으며, PBS 기반 보관용액에 포함되어 안정적입니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:5,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 5F2 |
| Immunogen | A synthesized peptide derived from human APC (UniProt ID: P25054-1, antigen range: 72–91) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 150 mM NaCl |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2898321 |
Product Specific Information
This antibody has been tested in direct ELISA.
Target Information
This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in processes such as cell migration, adhesion, transcriptional activation, and apoptosis.
Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that often progresses to malignancy.
Disease-associated mutations are clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: MA5-38407_Protein_APC_P25054-1_Rabbit.svg, MA5-38407_Protein_APC_P25054-1_Rabbit_PDP.jpeg)
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