Thermo Fisher Scientific NFATC3 Polyclonal Antibody
NFATC3 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. IHC 및 IHC(P) 실험에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS/glycerol buffer에 보관되며, 고순도(>95%)를 제공합니다.
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- PA536101
- 판매단위
- pk
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: Not specified
- View 1 publication
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- View publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 130–180 of human NFAT4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553368 |
Product Specific Information
- Detects endogenous NFATC3 protein at approximately 115 kDa.
- Purity: >95% by SDS-PAGE.
Target Information
This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance.
mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD).
When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons.
This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping.
Use of multiple polyadenylation sites has been noted for this gene.
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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