Thermo Fisher Scientific LOXL2 Polyclonal Antibody
Human LOXL2 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 등 다양한 연구용에 적합함. 항원 친화 크로마토그래피로 정제되었으며, PBS 버퍼와 sodium azide를 포함한 액상 형태로 제공됨. 장기 보관 시 -20°C에서 냉동 보관 권장.
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Thermo Fisher Scientific LOXL2 Polyclonal Antibody
Applications and Tested Dilution
- Immunohistochemistry (Paraffin) [IHC (P)]: 15 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 17 amino acid peptide from internal region of human LOXL2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550361 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Marmoset (100%)
Gorilla, Orangutan, Monkey, Bovine, Bat, Elephant (94%)
Dog, Panda, Horse, Opossum (88%)
Target Information
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyzes the first step in the formation of crosslinks in collagens and elastin.
A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function.
The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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