Thermo Fisher Scientific ABCE1 Polyclonal Antibody

Thermo Fisher Scientific ABCE1 Polyclonal Antibody

Applications

• Western Blot (WB): Tested dilution 0.1–0.5 µg/mL

Product Specifications

Product Specific Information

Human Bcl-XL shares 97.9% amino acid sequence identity with both mouse and rat Bcl-XL.
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.

Target Information

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters.
ABC proteins transport various molecules across extra- and intra-cellular membranes.
ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).
This protein is a member of the OABP subfamily and functions as an RNase L inhibitor, blocking ribonuclease L activity.
Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, central to viral interferon action.
Two transcript variants encoding the same protein have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.