Thermo Fisher Scientific CTLA4 Monoclonal Antibody (OTI3B11)
CTLA4 단백질을 표적으로 하는 Mouse IgG1 단클론 항체로 인간 시료에 반응합니다. Flow Cytometry에 1:400 희석으로 사용 가능하며, 무보존제 PBS와 트레할로스 완충액에 동결건조 형태로 제공됩니다. 연구용으로만 사용됩니다.
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Applications
- Flow Cytometry (Flow): Tested Dilution 1:400
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3B11 |
| Immunogen | Full length human recombinant protein of human CTLA4 (NP_005205) produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor mainly expressed on CD4+ T cells. It binds CD80 and CD86 ligands on B cells and dendritic cells with higher affinity than CD28. Unlike CD28, which enhances T-cell function, CTLA4 inhibits T-cell activity. Intracellular CTLA4 is also found in regulatory T cells and may be essential for their function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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