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Thermo Fisher Scientific SF1 Polyclonal Antibody
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Thermo Fisher Scientific SF1 Polyclonal Antibody는 인간 및 생쥐 시료에서 SF1 단백질 검출용 항체로, WB, IHC, IP 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 고순도 액상 형태로 제공됩니다.
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- pk
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마지막 업데이트 2025. 08. 05. 오전 10:25
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Thermo Fisher Scientific A303213AT SF1 Polyclonal Antibody 10 ul pk판매 단위 pk ·
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194,600원VAT 포함 214,060원
Thermo Fisher Scientific · Thermo Fisher Scientific SF1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 25 and 75 of Human Splicing Factor 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections.
Target Information
Splicing factor 1 (SF1) is a nuclear pre-mRNA splicing factor that specifically recognizes the intron branch point sequence at the 3′ splice site, together with the large subunit of U2 auxiliary factor (U2AF). It is required for early spliceosome assembly and plays roles in nuclear pre-mRNA retention and transcriptional repression.
The protein contains:
- N-terminal U2AF ligand motif
- Central hnRNP K homology motif and quaking 2 region (binds branch-site adenosine)
- Zinc knuckles domain
- C-terminal proline-rich domain
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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