Thermo Fisher Scientific MSI2 Polyclonal Antibody
MSI2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot 및 면역침전(IP)에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 인간 단백질에 반응. 줄기세포 유지 및 신경계 연구에 활용.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 200 and 250 of human Musashi Homolog 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
Target Information
Msi2 (Musashi homolog 2), also known as MSI2H, is a 328 amino acid RNA-binding protein localized in the cytoplasm and containing two RRM (RNA recognition motif) domains. It is expressed ubiquitously at low levels and plays a role in the proliferation and maintenance of stem cells within the central nervous system by regulating target mRNA expression. Msi2 is phosphorylated post-translationally and upregulated in response to brain injury, suggesting a role in neural regeneration. Chromosomal aberrations involving Msi2 are associated with chronic myeloid leukemia progression. Multiple isoforms exist due to alternative splicing.
Tissue specificity: Ubiquitous; detected at low levels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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