Thermo Fisher Scientific Cystatin C Polyclonal Antibody
Cystatin C 단백질을 타겟으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB, ICC/IF, ELISA에 적합하며 Human, Mouse, Rat 반응성. 고순도 Affinity Chromatography 정제, 액상 형태로 -20°C 보관. 연구용으로만 사용.
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Thermo Fisher Scientific Cystatin C Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:10–1:100 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–146 of human Cystatin C (NP_0000901) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.58 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2913951 |
Product Specific Information
Positive test controls include:
- SKOV3
- A-549
- BT-474
- HeLa
- Mouse liver
- Mouse testis
- Rat brain
The target is usually found in the following location: Secreted
Immunogen sequence:
MAGPLRAPLL LLAILAVALA VSPAAGSSPG KPPRLVGGPM DASVEEEGVR RALDFAVGEY NKASNDMYHS RALQVVRARK QIVAGVNYFL DVELGRTTCT KTQPNLDNCP FHDQPHLKRK AFCSFQIYAV PWQGTMTLSK STCQDA
Target Information
Cystatin C, a member of the type 2 cystatin superfamily, is a potent inhibitor of cysteine proteinases, both endogenous (lysosomal cathepsins) and pathogenic.
Cystatin C is a 13 kDa secreted protein found in high concentrations in biological fluids and expressed by all human nucleated cells.
Alterations in Cystatin C levels are linked to cardiovascular diseases such as atherosclerosis, amyloid angiopathy, and myocardial infarction.
Due to its low molecular weight, Cystatin C is also used as a marker of renal failure.
Usage Restriction
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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