Thermo Fisher Scientific NAGA Monoclonal Antibody (OTI3A4)
인간 NAGA 단백질을 인식하는 마우스 단클론 항체로, WB 및 IHC(P)에서 1:500 희석으로 사용 가능. HEK293T 세포에서 생산된 재조합 단백질을 면역원으로 사용. 고순도 친화 크로마토그래피 정제, 안정한 액상 형태로 연구용 적합.
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- MA527447
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Applications
- Western Blot (WB): 1:500
- Immunohistochemistry (Paraffin) (IHC (P)): 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3A4 |
| Immunogen | Full length human recombinant protein of NAGA produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724790 |
Target Information
NAGA (N-acetylgalactosaminidase, alpha), also known as alpha-galactosidase B or GALB, is a 411 amino acid lysosomal protein belonging to the glycosyl hydrolase 27 family. It may exist as a homodimer and plays a critical role in glycolipid breakdown.
NAGA encodes alpha-N-acetylgalactosaminidase, a lysosomal enzyme that cleaves alpha-N-acetylgalactosaminyl groups from glycoconjugates.
Mapping to human chromosome 22q13.2, NAGA defects cause an autosomal recessive disorder with three phenotypes, known as Schindler disease (types I, II, and III) or NAGA deficiency.
Schindler disease type I is the most severe form, type III has mild-to-moderate effects, and type II (Kanzaki disease) is characterized by mild intellectual impairment and angiokeratoma corporis diffusum.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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