Thermo Fisher Scientific NAGA Monoclonal Antibody (OTI3A4)

Applications

• Western Blot (WB): 1:500
• Immunohistochemistry (Paraffin) (IHC (P)): 1:500

Product Specifications

Target Information

NAGA (N-acetylgalactosaminidase, alpha), also known as alpha-galactosidase B or GALB, is a 411 amino acid lysosomal protein belonging to the glycosyl hydrolase 27 family. It may exist as a homodimer and plays a critical role in glycolipid breakdown.
NAGA encodes alpha-N-acetylgalactosaminidase, a lysosomal enzyme that cleaves alpha-N-acetylgalactosaminyl groups from glycoconjugates.
Mapping to human chromosome 22q13.2, NAGA defects cause an autosomal recessive disorder with three phenotypes, known as Schindler disease (types I, II, and III) or NAGA deficiency.
Schindler disease type I is the most severe form, type III has mild-to-moderate effects, and type II (Kanzaki disease) is characterized by mild intellectual impairment and angiokeratoma corporis diffusum.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.

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