Thermo Fisher Scientific IL-2 Monoclonal Antibody (MQ1-17H12), PE, eBioscience

Thermo Fisher Scientific IL-2 Monoclonal Antibody (MQ1-17H12), PE, eBioscience™

Applications

• Flow Cytometry (Intracellular staining)

Tested Dilution: 0.25 µg/test
Publications: View 23 publications

Product Specifications

Available Formats

• Unconjugated
• Alexa Fluor 532
• APC
• Brilliant UV 395
• Brilliant UV 615
• Brilliant UV 737
• Brilliant Violet 421
• Brilliant Violet 480
• eFluor 450
• FITC
• PE-Cyanine7
• PE-eFluor 610
• PerCP-eFluor 710
• Request custom conjugation

Product Specific Information

The MQ1-17H12 antibody reacts with human interleukin-2 (IL-2), a 17 kDa T-cell growth factor and major immunoregulatory cytokine.
This antibody is non-neutralizing and suitable for intracellular flow cytometric analysis.

Applications Tested:

• Intracellular staining of stimulated normal human peripheral blood cells
• Recommended usage ≤ 0.25 µg/test (100 µL final volume)
• Optimal titration recommended for best assay performance
• Excitation: 488–561 nm; Emission: 578 nm
• Compatible lasers: Blue, Green, Yellow-Green
• Filtration: 0.2 µm post-manufacturing filtered

Target Information

Interleukin 2 (IL-2) is an immunomodulatory cytokine critical for proliferation and differentiation of T cells, B cells, NK cells, monocytes, and macrophages.
IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric complex sharing the gamma chain with IL-4 and IL-7.
Monoallelic expression of IL-2 in mature thymocytes represents a unique gene regulation mechanism.
Disruption of IL-2-like genes in mice leads to colitis-like symptoms, underscoring its essential role in immune regulation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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