Thermo Fisher Scientific PSPN Polyclonal Antibody
인간 Persephin 단백질을 인식하는 Thermo Fisher Scientific의 다클론 항체로, IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 고순도 액상 형태로 제공됩니다. 신경영양 인자 연구 및 단백질 발현 분석에 활용 가능합니다.
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Thermo Fisher Scientific PSPN Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:25–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region derived from internal residues of human persephin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635983 |
Product Specific Information
This antibody detects endogenous levels of total Persephin protein.
Target Information
Persephin is a disulfide-linked, homodimeric neurotrophic factor structurally related to GDNF, artemin, and neurturin. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. Persephin signals through a multicomponent receptor system composed of RET and one of four GFR alpha (α1–α4) receptors. GFRα4 was first identified in chicken and later shown to be the preferential binding subunit for persephin. Persephin promotes the survival of ventral midbrain dopaminergic neurons and motor neurons after sciatic nerve axotomy, and like GDNF, promotes ureteric bud branching. However, unlike GDNF and neurturin, persephin does not support the survival of peripheral neurons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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