Thermo Fisher Scientific KCC3 Polyclonal Antibody
Rabbit polyclonal antibody against human KCC3 (SLC12A6) for IHC (Paraffin) applications. Detects endogenous KCC3 protein. Purified by antigen affinity chromatography. Supplied in PBS with 40% glycerol, stored at -20°C. For research use only.
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- PA550526
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- pk
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region derived from internal residues of human Solute carrier family 12 (potassium/chloride transporters), member 6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635979 |
Product Specific Information
The antibody detects endogenous levels of total KCC3 / SLC12A6 protein.
Target Information
SLC12A6 is a member of the K-Cl cotransporter (KCC) family. These integral membrane proteins help regulate intracellular chloride concentrations below the electrochemical equilibrium potential. The protein is activated by cell swelling under hypotonic conditions. Alternative splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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