Thermo Fisher Scientific Plectin Polyclonal Antibody
Rabbit polyclonal antibody targeting human Plectin-1. Validated for IHC (Paraffin) with 1:50–1:200 dilution. Detects endogenous total Plectin-1. Purified via antigen affinity chromatography and supplied in PBS with 40% glycerol. For research use only.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region derived from internal residues of human plectin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636183 |
Product Specific Information
This antibody detects endogenous levels of total Plectin-1 protein.
Target Information
Plectin is a major member of the plakin or cytolinker family, which interconnects different elements of the cytoskeleton. These large, multi-domain proteins are essential for maintaining cell and tissue integrity, regulating cytoarchitecture and cell shape, and serving as scaffolds for signaling complexes.
Plectin is expressed as multiple isoforms from a single gene on human chromosome 8. Isoform expression varies by cell type and developmental stage, with each isoform set contributing to distinct cellular functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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