Thermo Fisher Scientific PCDHB11 Polyclonal Antibody
Human PCDHB11 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 실험에 최적화되어 있습니다. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA550725
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region derived from internal residues of human protocadherin beta 11 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2636177 |
Product Specific Information
This antibody detects endogenous levels of total PCDHB11 protein.
Target Information
This gene is a member of the protocadherin beta gene cluster, one of three related clusters tandemly linked on chromosome 5. These clusters show genomic organization similar to B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding six extracellular cadherin domains and a cytoplasmic tail distinct from other cadherins. The extracellular domains mediate homophilic interactions, contributing to specific cell-cell connections. Unlike the alpha and gamma clusters, transcripts from these genes consist of a single large exon. These neural cadherin-like adhesion proteins are integral membrane proteins likely involved in establishing and maintaining specific neural connections.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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