Thermo Fisher Scientific THAP11 Monoclonal Antibody (364CT25.4.2)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:100-1:500

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Mouse / IgM

Class

Monoclonal

Type

Antibody

Clone

364CT25.4.2

Immunogen

KLH conjugated synthetic peptide between 165-193 amino acids from the Central region of human THAP11 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:THAP11,uniProtId:Q96EK4-1,ncbiNodeId:9606,antigenRange:165-193,antigenLength:314,antigenImageFileName:MA5-37544_THAP11_Q96EK4-1_House_mouse.svg,antigenImageFileNamePDP:MA5-37544_THAP11_Q96EK4-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Euglobulin precipitation

Storage buffer

PBS, pH 7.4

Contains

0.09% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2897474

Target Information

This gene encodes two proteins, the SART1protein expressed in the nucleus of the majority of proliferating cells, and the SART1protein expressed in the cytosol of epithelial cancers. The SART1protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation; its full-length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens. The SART1protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.