Thermo Fisher Scientific PKA beta Polyclonal Antibody
PKA beta 단백질을 인식하는 Rabbit Polyclonal 항체로, Human 시료에 반응합니다. IHC(P)에서 1:500~1:1,000 희석으로 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PRKACB. Recombinant protein control fragment (Product #RP-102341) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2790261 |
Product Specific Information
Immunogen sequence:
MAAYREPPCN QYTGTTTALQ KLEGFASRLF HRHSKGTAHD QKTALENDSL HFSEHTALWD RSMKEFLAKA KEDFLKKWEN PTQNNAGLED FER
Target Information
The catalytic subunit C-beta of PKA (PRKACB) is a member of the Ser/Thr protein kinase family. The PKA catalytic subunit consists of three gene products: C-alpha, C-beta, and C-gamma, and has been assigned to human chromosome region 1p36.1.
PRKACB is derived from a gene distinct from C-alpha and shows tissue-specific expression. At the amino acid level, C-alpha and C-beta show 93% homology.
The inactive holoenzyme of AMPK is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits of AMPK have been identified in humans.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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