Thermo Fisher Scientific CBX8 Monoclonal Antibody (OTI2A5), TrueMAB
Human CBX8 단백질(aa 1-260)에 특이적인 mouse monoclonal antibody. Western blot에서 검증됨. Lyophilized 형태로 제공되며, 재구성 후 1 mg/mL 농도. PRC1 복합체 관련 연구용으로 적합.
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Applications
- Western Blot (WB): 1:2,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2A5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–260 of human CBX8 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform additional desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
CBX8 is a component of the Polycomb group (PcG) multiprotein PRC1-like complex, which maintains the transcriptionally repressive state of many genes, including Hox genes, during development.
The PRC1 complex acts through chromatin remodeling and histone modification, mediating monoubiquitination of histone H2A at Lys-119, thereby altering chromatin expressibility.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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