Thermo Fisher Scientific HBS1L Monoclonal Antibody (OTI2A3), TrueMAB
Human HBS1L 단백질(aa 1-242)을 항원으로 한 Mouse IgG1 단클론 항체. Western blot에 최적화된 TrueMAB 형식으로 제공. Lyophilized 형태, PBS/trehalose buffer 포함, -20°C 보관. 연구용 전용 제품.
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Thermo Fisher Scientific HBS1L Monoclonal Antibody (OTI2A3), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution: 1:500
Publications: - References
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2A3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–242 of human HBS1L produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
The HBS1L gene encodes a member of the GTP-binding elongation factor family. It is expressed in multiple tissues, with highest expression in heart and skeletal muscle.
The intergenic region between HBS1L and MYB has been identified as a QTL controlling fetal hemoglobin levels and influencing erythrocyte, platelet, and monocyte counts, as well as erythrocyte volume and hemoglobin content.
DNA polymorphisms in this region are associated with fetal hemoglobin levels and pain crises in sickle cell disease.
A single nucleotide polymorphism in exon 1 is linked to severity in beta-thalassemia/Hemoglobin E.
Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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