Thermo Fisher Scientific Spastin Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

View 1 publication 1 publication

Immunoprecipitation (IP)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Published species

Not Applicable

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human Spastin. Recombinant protein control fragment (Product #RP-89991). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Spastin,uniProtId:Q9UBP0-1,ncbiNodeId:9606,antigenRange:234-371,antigenLength:616,antigenImageFileName:PA5-53581_Spastin_Q9UBP0-1_Rabbit.svg,antigenImageFileNamePDP:PA5-53581_Spastin_Q9UBP0-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.10 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2647785

Product Specific Information

Immunogen sequence: KRKDPLTHTS NSLPRSKTVM KTGSAGLSGH HRAPSYSGLS MVSGVKQGSG PAPTTHKGTP KTNRTNKPST PTTATRKKKD LKNFRNVDSN LANLIMNEIV DNGTAVKFDD IAGQDLAKQA LQEIVILPSL RPELFTGL

Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 91%.

Target Information

This gene encodes a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. The encoded ATPase may be involved in the assembly or function of nuclear protein complexes. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their full length sequences have not been determined. Mutations associated with this gene cause the most frequent form of autosomal dominant spastic paraplegia 4.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.