Thermo Fisher Scientific STING1/TMEM173 Monoclonal Antibody (STING1/7432)
인간 STING1/TMEM173 단백질을 인식하는 단클론 항체로, 면역조직화학(IHC)에 사용 가능. NF-κB 및 IRF3 경로 활성화 관련 연구에 적합. 단백질 A/G로 정제된 액상 항체이며, 4°C 보관. 연구용으로만 사용.
- 카탈로그번호
- 340061-MSM2-Px (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific STING1/TMEM173 Monoclonal Antibody (STING1/7432)
Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | STING1/7432 |
| Immunogen | Recombinant fragment (aa190–290) of human TMEM173 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
STING is a 379 amino acid signaling protein that plays a critical role in innate immune signaling. It activates NF-κB and IRF3 transcription pathways, inducing type I interferon expression (IFN-α and IFN-β) and promoting antiviral responses. STING may also function as a translocon, influencing interferon induction and apoptotic signaling through MHC-II association. It facilitates detection of intracellular viral RNA and B-form DNA and mediates death signaling via ERK pathway activation. STING is localized to the endoplasmic reticulum membrane, cell membrane, and mitochondrial outer membrane, and is ubiquitously expressed in most tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: 340061-MSM2-P0_STING_Q86WV6-1_House_mouse.svg / 340061-MSM2-P0_STING_Q86WV6-1_House_mouse_PDP.jpeg)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.