Thermo Fisher Scientific TRPV1 Polyclonal Antibody
TRPV1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 IHC에 적합합니다. 사람 유래 항원으로 제작되었으며, 비결합(Unconjugated) 형태로 제공됩니다. 단기 4°C, 장기 -20°C 보관 권장. 연구용 전용 시약입니다.
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- OST00087W-100UL
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunohistochemistry (IHC) | 1:1,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from human TRPV1 conjugated to blue carrier protein was used as the antigen |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: TRPV1.
Target Information
TRPV1 (Transient Receptor Potential Cation Channel Subfamily V Member 1) is a receptor for capsaicin, the main pungent ingredient in hot chili peppers, and elicits a sensation of burning pain by selectively activating sensory neurons.
TRPV1 is a non-selective cation channel related to TRP family members such as TRPC3 and TRPC6, permeable to calcium, magnesium, sodium, and potassium ions.
It contains six transmembrane domains, a P-loop membrane domain, and three ankyrin repeat domains. TRPV1 is activated by noxious heat and protons, functioning as a transducer of painful thermal stimuli in vivo.
Expression is mainly limited to sensory ganglia neurons. Four transcript variants have been identified with variations in the 5′ UTR sequence.
Diseases associated with TRPV1 include Irritable Bowel Syndrome (IBS) and Bladder Disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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