Thermo Fisher Scientific Thrombomodulin/CD141 Monoclonal Antibody (THBD, 1591)
인간 Thrombomodulin/CD141 단백질을 인식하는 Mouse 모노클로날 항체로, WB 및 IHC(P) 등에 사용 가능. Recombinant fragment(aa 69-194)를 면역원으로 제작. Protein A/G 정제, 200 µg/mL 농도의 액상 형태. 연구용으로만 사용.
- 카탈로그번호
- 7056-MSM1-P0
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL | |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | THBD, 1591 |
| Immunogen | Recombinant fragment (around aa 69–194) of human Thrombomodulin (CD141) protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 minutes at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
Thrombomodulin (TM), also known as Fetomodulin (FM), endothelial anticoagulant protein, or glycoprotein P112, contains six repeated domains homologous to epidermal growth factor (EGF) and an amino-terminal domain homologous to lectin-like protein.
Through its accelerated activation of protein C, TM synthesis is one of several mechanisms important in maintaining thrombo-resistance and reducing clot formation on endothelial surfaces.
Immunohistochemical staining of formalin-fixed tissue for TM has been used in studies of vascular tumors, meningiomas, and choriocarcinomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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