Thermo Fisher Scientific PSKH2 Polyclonal Antibody
Human PSKH2 단백질에 특이적인 Rabbit Polyclonal 항체로 Western blot 및 IHC(P) 검증 완료. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 세린/트레오닌 단백질 인산화 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PSKH2. Recombinant protein control fragment (Product #RP-91450). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646050 |
Product Specific Information
Immunogen sequence:
SGFLPFDDES QTRLYRKILK GKYNYTGEPW PSISHLAKDF IDKLLILEAG HRMSAGQALD HPWVITMAAG SSMKNLQRAI SRNLMQRASP HSQSPGSAQS SKSHYSHKSR
Sequence identity:
Highest antigen sequence identity to the following orthologs:
- Mouse: 62%
- Rat: 62%
Target Information
The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes including cell division, homeostasis and apoptosis.
A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases.
PSKH2 (protein serine kinase H2) is a 385 amino acid protein belonging to the CAMK Ser/Thr protein kinase family. It contains one protein kinase domain and is encoded by a gene located on human chromosome 8, which consists of nearly 146 million base pairs and houses more than 800 genes.
Defects in specific genes mapped to chromosome 8 are associated with disorders such as schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome, and certain leukemias and lymphomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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