Thermo Fisher Scientific IL-4 Polyclonal Antibody
IL-4 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. Western blot, IHC, ICC/IF 등 다양한 응용에 사용 가능하며, 고순도 Affinity chromatography로 정제되었습니다. PBS + 50% glycerol에 보관하며 -20°C에서 안정적입니다.
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Thermo Fisher Scientific IL-4 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human IL4 (Accession P05112), corresponding to amino acid residues N39–C89 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900052 |
Product Specific Information
Antibody detects endogenous levels of total IL4.
Target Information
Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells and serves as a ligand for the interleukin 4 receptor. IL-4 has broad immunoregulatory functions and also interacts with IL13 through shared receptor components. STAT6 plays a key role in mediating IL-4 signaling.
The IL-4 gene is located on chromosome 5q within a cytokine gene cluster containing IL-3, IL-5, IL-13, and CSF2. IL-4 and IL-13 are closely positioned and regulated by long-range elements over a 120 kb region. IL-4 delta 2 is a known splice variant of IL-4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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