Thermo Fisher Scientific ESAM Monoclonal Antibody (408519)
인간 ESAM 단백질을 인식하는 Mouse IgG2b 단일클론 항체로, ICC/IF 및 Flow Cytometry에 적합. 단백질 A/G로 정제된 동결건조 형태이며, PBS와 trehalose를 포함. 교차 반응 없음, 연구용으로만 사용.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 8–25 µg/mL
Flow Cytometry (Flow)
- Tested Dilution: 2.5 µg per million cells
- Publications: 1 publication available
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Mouse |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 408519 |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human ESAM (Gln30–Ala247) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2606177 |
Product Specific Information
- In direct ELISAs, no cross-reactivity with recombinant mouse ESAM is observed.
- Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
ESAM (Endothelial cell-selective adhesion molecule) is a 55-kDa membrane protein composed of two extracellular Ig domains, a single transmembrane domain, and a 120 amino acid cytoplasmic domain.
It is related to the junctional adhesion molecule (JAM) family and is expressed on endothelial cells and activated platelets.
ESAM at endothelial tight junctions regulates vascular permeability in response to agents such as VEGF or extravasating neutrophils.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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