Thermo Fisher Scientific PCSK9 Monoclonal Antibody (407119)
인간 및 생쥐 PCSK9 단백질을 검출하는 Rat IgG1 단클론 항체. Western blot 및 Immunoprecipitation에 최적화. Protein A/G로 정제된 동결건조 형태로 제공되며, 보존제 무첨가. 콜레스테롤 항상성 연구용으로 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunoprecipitation (IP) | 25 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rat / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 407119 |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant mouse Proprotein Convertase 9/PCSK9 (Gln35–Gln694) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2606592 |
Product Specific Information
This antibody detects the mature form of human and mouse Proprotein Convertase 9 (PCSK9) in direct ELISAs and Western blots.
It does not cross-react with recombinant human PC-1 or PC-7.
Reconstitute at 0.5 mg/mL in sterile PBS before use.
Target Information
PCSK9 is a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family.
It is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum.
PCSK9 plays a key role in cholesterol homeostasis and may be involved in cortical neuron differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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