Thermo Fisher Scientific WIPI1 Polyclonal Antibody
WIPI1 단백질을 인식하는 Thermo Fisher의 토끼 폴리클로날 항체로, Western blot에 최적화되어 있습니다. 인간 및 마우스에 반응하며, 자가포식 관련 연구에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol 용액 형태로 제공됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:10,000
- View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 356–446 of WIPI1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2552322 |
Product Specific Information
- Recommended positive controls: human WIPI1-transfected 293T cells, mouse muscle
- Predicted reactivity: Mouse (100%), Rat (100%), Pig (100%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly before opening the vial.
Target Information
WIPI1 (WD repeat domain, phosphoinositide interacting-1), also known as WIPI1, ATG18, or WIPI49, is thought to play a role in autophagy and may regulate protein trafficking in certain recycling pathways. It contains three WD repeats and has a 7-bladed propeller structure with a conserved motif that facilitates its interaction with other proteins. WIPI1 localizes to cytoplasmic vesicles, endosomes, clathrin-coated vesicles, and the trans-Golgi network. It is ubiquitously expressed, with highest expression in heart, testis, placenta, pancreas, and skeletal muscle. WIPI1 is upregulated in various tumors, suggesting a role in carcinogenesis.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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