Thermo Fisher Scientific WIPI1 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:10,000
• View 2 publications

Product Specifications

Product Specific Information

• Recommended positive controls: human WIPI1-transfected 293T cells, mouse muscle
• Predicted reactivity: Mouse (100%), Rat (100%), Pig (100%), Bovine (100%)
• Store product as a concentrated solution. Centrifuge briefly before opening the vial.

Target Information

WIPI1 (WD repeat domain, phosphoinositide interacting-1), also known as WIPI1, ATG18, or WIPI49, is thought to play a role in autophagy and may regulate protein trafficking in certain recycling pathways. It contains three WD repeats and has a 7-bladed propeller structure with a conserved motif that facilitates its interaction with other proteins. WIPI1 localizes to cytoplasmic vesicles, endosomes, clathrin-coated vesicles, and the trans-Golgi network. It is ubiquitously expressed, with highest expression in heart, testis, placenta, pancreas, and skeletal muscle. WIPI1 is upregulated in various tumors, suggesting a role in carcinogenesis.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.