
Thermo Fisher Scientific hnRNP H1 Polyclonal Antibody
Western blot, IHC, ICC/IF에 적합한 hnRNP H1 폴리클로날 항체. Human 및 Mouse 반응성. 항원 친화 크로마토그래피로 정제된 1 mg/mL 액상 제품. 4°C 단기 보관, -20°C 장기 보관 권장. 연구용으로만 사용.
- 카탈로그번호
- PA527610
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:5,000–1:20,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 50–289 of Human hnRNP H1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2545086 |
Product Specific Information
- Recommended positive controls: A431, H1299, HeLa, HepG2, Raji, NCI-H929, mouse brain
- Predicted reactivity: Mouse (100%), Rat (99%), Zebrafish (87%), Xenopus laevis (91%), Chicken (96%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a member of a subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins that complex with heterogeneous nuclear RNA and are associated with pre-mRNAs in the nucleus, influencing pre-mRNA processing and other aspects of mRNA metabolism and transport. While most hnRNPs are nuclear, some shuttle between the nucleus and cytoplasm. The hnRNP H1 protein contains three quasi-RRM domains that bind RNA and shares similarity with HNRPF. This gene may be associated with hereditary lymphedema type I, and alternatively spliced transcript variants have been described.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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