Thermo Fisher Scientific ATOH1 Recombinant Rabbit Monoclonal Antibody (JE60-25)
ATOH1 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot에 최적화됨. Mouse와 Rat 시료에 반응하며 HEK293 발현 시스템에서 생산. 고순도 Protein A 정제 및 안정적인 액상 형태로 제공. 신경세포 분화 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JE60-25 |
| Immunogen | Synthetic peptide within human MATH1 aa 1–50/354 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 0.05% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2931286 |
Target Information
The Drosophila atonal gene produces a protein with basic helix-loop-helix (bHLH) domains that plays an essential role in the development of the Drosophila nervous system.
Mammalian atonal homolog 1 (MATH-1, also known as Atoh1, Ath1, or HATH-1) is a 351 amino acid protein with an atonal-related basic HLH domain.
In mice, expression of MATH-1 begins by embryonic day 9.5 and localizes to cranial ganglions and the dorsal part of the central nervous system.
By day 18, expression becomes restricted to the external granular layer of the cerebellum and is undetectable in the adult nervous system.
MATH-1 may play a role in the differentiation of subsets of neural cells by activating E box-dependent transcription.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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