Thermo Fisher Scientific PAX6 Monoclonal Antibody (7H10.D3.D4.G5)
인간 PAX6 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot, ICC/IF, ELISA에 적합합니다. 단백질 A로 정제된 액상형 제품이며 -20°C 보관을 권장합니다. 신경계 및 안구 발달 관련 연구에 활용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| ELISA | 1:75,000–1:150,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 7H10.D3.D4.G5 |
| Immunogen | Recombinant human PAX6 protein (1–422 aa) used for immunization in mice |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Store vial at -20°C prior to opening.
- Aliquot contents and refreeze at -20°C or below for long-term storage.
- Avoid repeated freeze/thaw cycles.
- Centrifuge if solution is not clear after standing at room temperature.
- Stable for several weeks at 4°C as undiluted liquid.
- Dilute only prior to immediate use.
- Cross-reactivity with PAX6 from other species has not been determined.
Target Information
The PAX6 gene encodes paired box gene 6, a human homolog of the Drosophila gene prd. It contains both a paired box domain and a homeobox domain, which bind DNA and regulate transcription. PAX6 is expressed in the developing nervous system and eyes. Mutations in PAX6 are associated with ocular disorders such as aniridia and Peter’s anomaly. Alternative splicing results in different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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