Thermo Fisher Scientific ME2 Monoclonal Antibody (970CT2.1.1.2)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:4,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:25

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

970CT2.1.1.2

Immunogen

KLH conjugated synthetic peptide between 522-556 amino acids from the C-terminal region of human ME2 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ME2,uniProtId:P23368-1,ncbiNodeId:9606,antigenRange:522-556,antigenLength:584,antigenImageFileName:MA5-37745_ME2_P23368-1_House_mouse.svg,antigenImageFileNamePDP:MA5-37745_ME2_P23368-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Protein G

Storage buffer

PBS, pH 7.4

Contains

0.09% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2897669

Target Information

ME2 encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.