Thermo Fisher Scientific ME2 Monoclonal Antibody (970CT2.1.1.2)
ME2 단백질을 인식하는 Mouse monoclonal 항체로, Western blot과 IHC(Paraffin)에서 검증됨. Human 및 Mouse 시료에 반응하며, Protein G로 정제된 액상 형태. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:25 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 970CT2.1.1.2 |
| Immunogen | KLH conjugated synthetic peptide between 522–556 amino acids from the C-terminal region of human ME2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein G |
| Storage buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897669 |
Target Information
ME2 encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein that catalyzes the oxidative decarboxylation of malate to pyruvate. It was previously weakly linked to Friedreich ataxia, which is now known to result from a mutation in a different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been associated with increased risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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