Thermo Fisher Scientific STUB1 Monoclonal Antibody (1008CT12.4.1)
STUB1 단백질을 인식하는 Mouse 모노클로날 항체로 Western blot에 최적화됨. Human 및 Mouse 시료에 반응하며, Protein G로 정제된 액상 형태. 장기 보관 시 -20°C에서 안정적이며 연구용으로 사용 가능.
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- MA537751
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- pk
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Thermo Fisher Scientific STUB1 Monoclonal Antibody (1008CT12.4.1)
Applications
- Western Blot (WB)
Tested Dilution: 1:4,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1008CT12.4.1 |
| Immunogen | Recombinant protein of human STUB1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897675 |
Target Information
A recently identified protein, termed carboxyl terminus of hsc70-interacting protein (CHIP), interacts with both the constitutive form of hsc70 and the stress-inducible form, hsp70. This 35 kDa cytoplasmic protein is highly expressed in striated muscle and across a broad range of cultured tissues. Through immunoprecipitation experiments, CHIP directly binds to the carboxyl terminus of hsc70 and hsp70, decreasing ATPase activity and reducing overall chaperone efficiency. It also functions as an E3 ubiquitin-ligase within the ubiquitin-proteasome system, containing a U-box domain and acting in conjunction with hsc70 and hsp90.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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