Thermo Fisher Scientific G6PD Recombinant Rabbit Monoclonal Antibody (JA31-40)
G6PD 단백질을 인식하는 재조합 토끼 단일클론 항체로, Western blot, IHC, ICC/IF, Flow Cytometry 등에 사용 가능. 높은 특이성과 감도를 제공하며, 로트 간 일관성이 우수함. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JA31-40 |
| Immunogen | Synthetic peptide within Human Glucose 6 Phosphate Dehydrogenase (aa 460–509) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809958 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning specific antibody DNA sequences from immunoreactive rabbits, followed by screening of individual clones to select optimal candidates for production.
Advantages include:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
The G6PD gene encodes glucose-6-phosphate dehydrogenase, a cytosolic enzyme that produces NADPH — a key electron donor for defense against oxidizing agents and reductive biosynthesis.
This X-linked housekeeping gene shows high genetic diversity, with many variants caused by missense mutations leading to differing enzyme activity and clinical symptoms such as neonatal jaundice, acute hemolysis, or chronic non-spherocytic hemolytic anemia.
Two transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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