Thermo Fisher Scientific ADFP Polyclonal Antibody
Rabbit polyclonal antibody against human ADFP, suitable for WB, IHC, and Flow Cytometry. Recognizes internal region (residues 150–250) of ADFP. Predicted to cross-react with rat. Supplied as liquid, 1.23 mg/mL, store at -20°C.
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- PA116971
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | Assay-dependent |
| Flow Cytometry (Flow) | 2.5 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the internal region (within residues 150–250) of human ADFP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.23 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_821789 |
Product Specific Information
This antibody is predicted to react with rat based on 84% sequence homology.
Target Information
Milk lipid globules from humans, cows, and rats contain a protein identified as adipocyte differentiation-related protein (ADFP). It is associated with the globule surface membrane material.
This protein, previously believed to be specific to adipocytes, is a major constituent of the globule surface and is present in a detergent-insoluble complex that contains butyrophilin and xanthine oxidase.
ADFP (Adipophilin) is found in a wide range of cultured cell lines, including fibroblasts, endothelial, and epithelial cells. In tissues, expression of adipophilin is restricted to specific cell types such as:
- Lactating mammary epithelial cells
- Adrenal cortex cells
- Sertoli and Leydig cells of the male reproductive system
- Steatosis or fatty change hepatocytes in alcoholic liver cirrhosis
ADFP may serve as a marker for identifying specialized differentiated cells containing lipid droplets and for diseases associated with fat-accumulating cells.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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