Thermo Fisher Scientific CD52 Chimeric Recombinant Rat Monoclonal Antibody (Campath-1H)
CD52 단백질을 인식하는 키메라 재조합 Rat 모노클로날 항체로, 다양한 면역학적 응용에 사용 가능. 인간 및 영장류 시료에 반응하며, HEK293 세포에서 발현된 IgG2b 타입 항체. WB, IHC, Flow cytometry, ELISA 등 다중 실험에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent |
| Flow Cytometry (Flow) | Assay-dependent |
| ELISA | Assay-dependent |
| Functional Assay | Assay-dependent |
| Cytotoxicity Assay (CT) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Cynomolgus monkey, Human, Rhesus monkey |
| Host / Isotype | Rat / IgG2b, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | Campath-1H |
| Immunogen | Human lymphocytes |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
Product Specific Information
Human CD52 antigen, also known as CAMPATH-1, is expressed at high density by lymphocytes, monocytes, eosinophils, thymocytes, and macrophages. It is expressed by most lymphoid-derived malignancies, although expression on myeloma cells is variable.
Target Information
CD52, also known as CAMPATH-1 antigen, is a glycoprotein expressed on the surface of various immune cells including T and B lymphocytes, natural killer cells, and monocytes. It plays a role in immune regulation and is a potential therapeutic target in diseases such as multiple sclerosis, chronic lymphocytic leukemia, and autoimmune disorders. CD52 is the target of alemtuzumab, a monoclonal antibody used to deplete immune cells expressing CD52.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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