Thermo Fisher Scientific CD52 Chimeric Recombinant Rabbit Monoclonal Antibody (HI186)
인간 CD52 단백질을 표적으로 하는 키메릭 재조합 토끼 단클론 항체. Western blot, IHC, ICC/IF, 유세포분석에 사용 가능. 단백질 A 정제, 1 mg/mL 농도, PBS 버퍼에 ProClin 300 포함. 면역세포 표면 단백질 연구용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | HI186 |
| Immunogen | Human tonsil cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
Product Specific Information
This antibody binds to human CD52.
Target Information
CD52, also known as CAMPATH-1 antigen, is a glycoprotein expressed on the surface of various immune cells, including T and B lymphocytes, natural killer cells, and monocytes. It plays a role in immune regulation and is a therapeutic target in diseases such as multiple sclerosis, chronic lymphocytic leukemia, and autoimmune disorders. CD52 is the target of alemtuzumab, a monoclonal antibody used to deplete CD52-expressing immune cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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