Thermo Fisher Scientific SUR1 Monoclonal Antibody (N289/16), FITC
SUR1 단백질을 인식하는 FITC 결합 마우스 단클론 항체로, WB, IHC, ICC/IF에 적합합니다. 다양한 종(햄스터, 인간, 마우스, 랫드)에 반응하며, 단백질 G로 정제된 액상 형태입니다. 4°C 어둠에서 보관하며 연구용으로 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (IHC) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Hamster, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N289/16 |
| Immunogen | Fusion protein amino acids 1548–1582 (cytoplasmic C-terminus) of rat SUR1 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 9.09 mM sodium bicarbonate/PBS, pH 7.4, with 640.91 mM DMSO, 136.36 mM ethanolamine |
| Contains | No preservative |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932013 |
Additional Formats Available
- Unconjugated (MA5-27660)
- APC (MA5-45558)
- PE (MA5-45561)
- PerCP (MA5-45560)
- Custom conjugation available upon request
Product Specific Information
- 1 µg/mL of MA5-45559 detects SUR1 in 20 µg of mouse brain membrane lysate by colorimetric immunoblot using goat anti-mouse IgG:HRP as secondary antibody.
- Detects approximately 160 kDa.
- Does not cross-react with SUR2B.
- Formerly sold as clone S289-16.
Target Information
The SUR1 protein belongs to the ATP-binding cassette (ABC) transporter superfamily. These proteins mediate transport of various molecules across cellular membranes. SUR1 functions as a modulator of ATP-sensitive potassium channels and insulin release.
Mutations in this gene are associated with hyperinsulinemic hypoglycemia of infancy and type II diabetes mellitus. Alternative splicing variants exist but are not fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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