Thermo Fisher Scientific SUR1 Monoclonal Antibody (N289/16), PerCP

Applications and Tested Dilution

Product Specifications

Available Formats

• Unconjugated
• APC
• FITC
• PE
• Request custom conjugation

Product Specific Information

• 1 µg/mL of MA5-45560 was sufficient for detection of SUR1 in 20 µg of mouse brain membrane lysate.
• Detection performed by colorimetric immunoblot using goat anti-mouse IgG:HRP as secondary antibody.
• Detects approximately 160 kDa.
• Does not cross-react with SUR2B.
• This antibody was formerly sold as clone S289-16.

Target Information

The protein encoded by this gene belongs to the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes and are divided into seven distinct subfamilies. This protein is part of the MRP subfamily involved in multi-drug resistance and functions as a modulator of ATP-sensitive potassium channels and insulin release.
Mutations or deficiencies in this protein are linked to hyperinsulinemic hypoglycemia of infancy and non-insulin-dependent diabetes mellitus type II. Alternative splicing has been observed, but transcript variants are not fully described.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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